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Health and safety: Difference between revisions
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As recently presented, MRPs have exhibited important beneficial health effects, such as antiradical, antimutagenic, antimicrobial, antihypertensive, antiallergenic, antioxidant, and cytotoxic properties (Rufian-Henares and Morales 2007; Wang and others ´ 2011; Echavarr´ıa and others 2012; Langner and Rzeski 2014; Pastoriza and Rufian-Henares 2014).<ref name=cargon>Carvalho DO, Gonçalves LM, Guido LF. [https://ift.onlinelibrary.wiley.com/doi/abs/10.1111/1541-4337.12218 Overall antioxidant properties of malt and how they are influenced by the individual constituents of barley and the malting process.] ''Compr Rev Food Sci Food Saf.'' 2016;15(5):927–943.</ref> | As recently presented, MRPs have exhibited important beneficial health effects, such as antiradical, antimutagenic, antimicrobial, antihypertensive, antiallergenic, antioxidant, and cytotoxic properties (Rufian-Henares and Morales 2007; Wang and others ´ 2011; Echavarr´ıa and others 2012; Langner and Rzeski 2014; Pastoriza and Rufian-Henares 2014).<ref name=cargon>Carvalho DO, Gonçalves LM, Guido LF. [https://ift.onlinelibrary.wiley.com/doi/abs/10.1111/1541-4337.12218 Overall antioxidant properties of malt and how they are influenced by the individual constituents of barley and the malting process.] ''Compr Rev Food Sci Food Saf.'' 2016;15(5):927–943.</ref> | ||
Phenolic acids, among all classes of phenolic compounds in foodstuffs (including barley and beer), are the most easily absorbed from the intestinal tract41,45. Phenolic acids from foods have been detected in urine9 and are present in blood in considerable concentrations13. Even when the consumption of more complex phenolic compounds is high, they are degraded and simple phenolic acids are excreted.<ref name=szw>Szwajgier D. [https://onlinelibrary.wiley.com/doi/10.1002/j.2050-0416.2009.tb00376.x Content of individual phenolic acids in worts and beers and their possible contribution to the antiradical activity of beer.] ''J Inst Brew.'' 2009;115(3):243–252.</ref> ferulic acid, the main phenolic acid in barley and beer, is present in the esterified form, but an esterase activity of bacterial origin is present in the human gastrointestinal tract | Phenolic acids, among all classes of phenolic compounds in foodstuffs (including barley and beer), are the most easily absorbed from the intestinal tract41,45. Phenolic acids from foods have been detected in urine9 and are present in blood in considerable concentrations13. Even when the consumption of more complex phenolic compounds is high, they are degraded and simple phenolic acids are excreted.<ref name=szw>Szwajgier D. [https://onlinelibrary.wiley.com/doi/10.1002/j.2050-0416.2009.tb00376.x Content of individual phenolic acids in worts and beers and their possible contribution to the antiradical activity of beer.] ''J Inst Brew.'' 2009;115(3):243–252.</ref> ferulic acid, the main phenolic acid in barley and beer, is present in the esterified form, but an esterase activity of bacterial origin is present in the human gastrointestinal tract. | ||
Oxidative stress is involved in the pathology of several human diseases, such as atherosclerosis, diabetes, neurodegenerative diseases, ageing, and cancer [1]. Dietary antioxidants can counteract the negative effects of oxidative stress. Polyphenols are the most abundant dietary antioxidants, due to their presence in all fruits and vegetables [1]. Polyphenol intake can be several hundreds of milligrams per day, up to 1 g/day, depending on dietary habits [2] and, in particular, in wine, coffee, beer, chocolate, and tea consumption; and it largely exceeds that of other antioxidants, such as vitamin E, vitamin C, and β-carotene [3]. Among polyphenols, phenolic acids account for about one-third of the total intake, while flavonoids account for the remaining two-thirds of the total intake [2]. Epidemiological studies have suggested associations between long-term consumption of polyphenols-rich foods and prevention of oxidative stress-related diseases such as cancer, cardiovascular diseases, diabetes, inflammation, and degenerative diseases [1,4–6].<ref>Nardini M, Foddai MS. [https://www.mdpi.com/1420-3049/25/11/2466 Phenolics Profile and Antioxidant Activity of Special Beers.] ''Molecules.'' 2020;25(11):2466.</ref> | |||